Scientific basics

Phylogeny of modern humans in Europe:

about how close relatives we are. 

phyloclip

Made with FigTree v.1.0 from an ClustalX-Alignment of 23S-rDNA Sequences queried from Genbank

Genetic Testing - the basic idea

Genetic Testing - the basic idea

As mitochondria are passed along the matrilineal path of heritage, mitochondrial DNA contains the memory of human ancestry. A close look at specific regons gives insight into this mystery. Most analysis is based on the d-loop region, where selection on mutations is lesser than in coding regions.…

Sequencing

Sequencing

--some SANGER related information with links to animation and hotpots--



Genetics Testing by AFLP  for Clade Ursula

Genetics Testing by AFLP for Clade Ursula

Based on the findings, that there are specific REnzyme cutting sites present or absent defining membership to a specific clade ( see "Genetic testing - the idea")
subsequent PCR-reactions for the most abundant clades were performed.


 For the Clade U we amplified the mitochondrial DNA from
pos.…

Matrilineal inheritance of mitochondrial DNA

Matrilineal inheritance of mitochondrial DNA

When combining genetic material forming a descendant, extrachromosomal DNA located in the parents mitochondria are not combined. The sperm's mittochondria do not enter the egg cell and if ever one gets through, it's eradicated. Therefore only the mother's extrachromosomal DNA is passed to the next…

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